The Ultimate Guide To https://www.ceesdekker.net
The Ultimate Guide To https://www.ceesdekker.net
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Midway through his job, Cees Dekker reinvented himself. Following yrs of hardcore physics, he shifted his target to ‘nanobiology’ within the change of your millennium. A phrase he coined himself, for a make a difference of actuality.
Human Rad51 filaments on double- and solitary-stranded DNA: correlating frequent and irregular types with recombination purpose.
[Laughs] ‘It absolutely was unquestionably a terrific chance! At time, I was nicely aware that it could go wrong and that I could grow to be much less profitable, but I just overlooked that. Curiosity has constantly been my strongest driving power. And luckily everything labored out.’
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
This yielded a breakthrough. In only a few months, we ended up in the position to evaluate transport as a result of a person solitary-walled carbon nanotube. According to small-temperature experiments by a brilliant PhD university student in my team, Sander Tans (now a valued colleague and professor at Delft University of Technologies having an active investigate lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with incredibly extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Electrical transportation in ceesdekker monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
‘In the beginning we checked out Organic systems using a Bodily perspective and acted on the basis on the applications we knew. It took a couple of years ahead of we begun working far more on the massive Organic issues. I then started to get in touch with it nanobiology, a expression that didn't exist at some time.
2011, initially in vitro measurements of transportation across just one biomimetic nuclear pore sophisticated; growth of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the mechanism of homology recognition in DNA homologous recombination
2003, demonstrated the first biosensors made outside of a carbon nanotube; resolved the structure and system of DNA mend proteins; and discovery of a different strategy for fabricating reliable-state nanopores for DNA translocation
Bulk-area coupling identifies the mechanistic connection in between Min-protein patterns in vivo and in vitro
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Nanoscientist Cees Dekker can be an amiable and flamboyant male who seems Significantly younger than the sixty two decades he actually is – modern glasses, psychedelic shirt, engaging smile – although not one particular to waste time. He takes his time, but not more than needed.
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Illustration (2) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is shown in gray, the rim from the pore is highlighted in purple, along with a 3D rendering with the motion on the DNA rod is displayed.